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Jack Sisson's TBI Blog
A hug is duct tape for the soul.
Tuesday, November 29, 2011
Article Highlights Widespread Nature of Drug-Induced Parkinsonism
We're featuring this article that's more than a year old because Jack recently discovered that he suffered from drug-induced Parkinsonism, and not the Parkinson's Disease with which he'd been diagnosed. Several weeks after eliminating the offending drug(s), his symptoms have either disappeared or greatly improved, and he feels 100% better.
From Public Citizen (Oct. 4, 2010)
Condition Is Frequently Misdiagnosed, Can Be Caused by 49 Drugs Listed on WorstPills.org
WASHINGTON, D.C. – A new article published in WorstPills.org highlights the widespread nature of drug-induced Parkinsonism and the need for patients and doctors to be aware of the potential to be misdiagnosed. The article includes a list of 49 prescription drugs known to cause drug-induced Parkinsonism.
Recent information has established that as many as one of every 10 people who went to a Parkinson’s disease center were found to have drug-induced Parkinsonism, not the more serious disease it is often mistaken for.
The people were misdiagnosed as having the more common illness, Parkinson’s disease, which is irreversible and has unknown causes. Drug-induced Parkinsonism, however, is reversible and is brought on by medication use.
“The bad news is that too many doctors do not know about the diseases’ differences, are inadequately aware of drug-induced Parkinsonism and therefore do not get a careful history from the patient about what drugs they started before the onset,” said Dr. Sidney Wolfe, director of Public Citizen’s Health Research Group and editor of WorstPills.org. “Doctors then mistake drug-induced Parkinsonism for the more commonly occurring Parkinson’s disease.”
This means that instead of suspecting a drug-induced origin and stopping the offending drug, doctors may mistakenly treat drug-induced Parkinsonism with another drug — as though they were treating Parkinson’s disease — while leaving the patient on the drug that caused the illness in the first place, Wolfe said.
Aging can make one prone to drug-induced Parkinsonism, and older people may be especially sensitive to drug-induced Parkinsonism from antipsychotic drugs. Also, almost 100 percent of people infected with HIV will get drug-induced Parkinsonism if given antipsychotic drugs, the article said.
Some symptoms of Parkinsonism that can distinguish it from Parkinson’s disease include:
• Symptoms on both the left and right sides (with Parkinson’s disease, the symptoms are typically on only one side);
• Symptoms end once the drug is no longer used (Parkinson’s disease is chronic and progressive); and
• No degeneration in the brain (Parkinson’s disease causes brain degeneration in a specific area).
Worst Pills, Best Pills, a monthly newsletter published by Public Citizen that offers an unbiased analysis of information from a variety of sources, is available in print and electronic formats at www.WorstPills.org. The site has other searchable information about the uses, risks and adverse effects associated with prescription medications.
Saturday, November 26, 2011
Tiny service dog heals Hampshire Marine
From the Chicago Daily Herald:
Thursday, November 24, 2011
On this day when we pause to think about what we have to be thankful for, we are humbled by our blessings.
Wednesday, November 23, 2011
Korean Robots Help Prevent Dementia
I have to admit I read that headline more than once, and the article too. Sounds like another instance of truth being stranger than fiction.
From Arirang, Korea's Global TV:
Meet Silbut, a robot designed to ward off Alzheimer's disease.
It's running a sing-along class and asking the attendants to fill in the blanks of the lyrics. Another robot dubbed Mero tells a story making various and subtle facial expressions. It gives compliments for correct answers and even makes jokes.
All of you here today look so nice. You're also good at answering the quizes.
This is a pilot class for training the brain using robots developed by the Korea Institute of Science and Technology. The aim is to prevent dementia by stimulating the brain with games.
"Due to aging, I tend to forget things a lot these days. I was wondering what I could do to prevent that and having tried this program, I think it's great."
At the moment, there are 16 games developed for seniors in their 60s to 70s. They are specifically designed to stimulate the three areas of the brain that are in charge of decision-making, making calculations and storing memory.
Under the program, these participants will take an evaluation test in December which marks the third month of training. The test results will be used to determine the level of progress in cognitive ability.
Recently, the authorities have sent 8 robots to Finland and Denmark after signing a collaborative agreement. And after a local three-month program and assessment, hopes are high that the Korean-made robots will make inroads into the overseas market.
"The robots are cost-effective and productive. For instance high skilled workers would not be able to go and care for seniors in remote areas. In such cases, robots could take their place."
As the next project, KIST plans to develop robots for the specially challenged children and for science education.Read at original source.
Monday, November 21, 2011
Warrior Beach founder lobbies for hyperbaric treatment
Sunday, November 20, 2011
Suicide Risk Greatest Early After Dementia Diagnosis
From MedScapeToday :
Receiving a diagnosis of dementia increases a person's risk for suicide, particularly if symptoms of depression and anxiety are present, a new study finds.
There is growing evidence that depression and anxiety are more likely to occur early in the course of dementia, which may drive suicidal behavior, Lisa S. Seyfried, MD, from the Department of Psychiatry, University of Michigan, Ann Arbor, and colleagues note in an article published in the November issue of Alzheimer's & Dementia.
"Timely identification and intervention addressing the complex issues of depression and dementia in these patients may help to mitigate their increased risk," they say.
"I think that we have to start conceptualizing dementia in a similar way to cancer," Professor Brian Draper, MBBS, MD, FRANZCP, from the School of Psychiatry, University of New South Wales, Sydney, Australia, who was not involved in the study, told Medscape Medical News.
"Some are already mildly depressed at the time of diagnosis. It is usually in that context that suicidal behavior occurs in the early months after diagnosis. A similar pattern is noted after cancer diagnosis, even when the prognosis might not be too bad," Dr. Draper said.
Continue reading (might have to register for a free account).
Friday, November 18, 2011
Why Brain Injuries Are More Common In Preemies
From Shots, NPR's Health Blog:
Scientists say they are beginning to understand why brain injuries are so common in very premature infants — and they are coming up with strategies to prevent or repair these injuries.The advances could eventually help reduce the number of premature babies who develop cerebral palsy, epilepsy or behavioral disorders such as ADHD, researchers told the Society for Neuroscience meeting in Washington, D.C., this week.
Each year more than 60,000 babies are born weighing less than 3.3 pounds. And because of advances in neonatal medicine over the past several decades, most of those babies will survive. But researchers have had less success finding ways to prevent brain damage in these infants.
The most common cause of brain injury in premature infants is a lack of oxygen in the days and weeks after birth, Rowitch says. The lack of oxygen damages white matter, which provides the "communication highways" that carry messages around the brain and to distant parts of the body, he says.
Continue reading.Those stresses often include periods when an infant's immature lungs are not delivering enough oxygen to the brain, even with help from a mechanical breathing device.
Tuesday, November 15, 2011
Depression May Be Precursor to Dementia
From Psych Central:
Depression is one of the most common mental disorders in the elderly, but little is known about the underlying biology of its development in older adults.
Tresearchers from the University of California, Los Angeles (UCLA) used a brain scan to assess the levels of amyloid plaques and tau tangles in older adults with major depressive disorder, also known as clinical depression.
Previous research has suggested that plaque and tangle deposits in the brain — hallmarks of Alzheimer’s disease and many dementias — are associated not only with memory loss but also with mild symptoms of depression and anxiety in middle-aged and older individuals.
The team wanted to see what the brain-scanning technique would find in older people with depression.
The researchers created a chemical marker called FDDNP that binds to both plaque and tangle deposits, which can then be viewed through a positron emission tomography (PET) brain scan, providing a “window into the brain.” Using this method, researchers are able to pinpoint where in the brain these abnormal protein deposits are accumulating.
The scientists compared the FDDNP brain scans of 20 older adults between the ages of 60 to 82 who had been diagnosed with depression with the scans of 19 healthy people of similar age, education and gender.
They found that in patients with depression, FDDNP binding was significantly higher throughout the brain and in critical brain regions. The critical brain regions included the posterior cingulate and lateral temporal areas, which are involved in decision-making, complex reasoning, memory and emotions...
...Researchers also found that similar protein deposit patterns in the lateral temporal and posterior cingulate areas in patients were associated with different clinical symptoms. Some patients demonstrated indicators of depression only, while others also displayed symptoms of mild cognitive impairment.
Dr. Small noted that previous research has shown that depression may be a risk factor for or a precursor to memory loss, such as mild cognitive impairment, which can later lead to dementia.
“We may find that depression in the elderly may be an initial manifestation of progressive neurodegenerative disease,” said the study’s first author, Dr. Anand Kumar, the Lizzie Gilman Professor and department head of psychiatry at the University of Illinois at Chicago.
Saturday, November 12, 2011
How to Cut Your Risk of Memory Loss
From CNN Health:
When Darla Arni's mother began showing the first signs of dementia 16 years ago, Arni worried she was doomed to the same fate.
So Arni began reading up on what she could do to stay mentally sharp. Turns out, plenty.
Arni, now 55, grew up on a farm where her mother fried just about everything in lard. Today, she skips the fried foods and eats plenty of fruits and vegetables, takes fish oil pills, goes for regular walks and meditates during a weekly yoga class.
And what's the point?
Doctors who specialize in the aging brain say that dementia is not inevitable, even in very old age. Making positive lifestyle changes earlier in life, they say, can lessen the chances of the faulty thinking and flagging memory that often come with advancing years.
Dr. Gary Small, director of UCLA's Longevity Center, says lifestyle may play a bigger role than genetics when it comes to who will fall into what he calls the "mental fog" of dementia.
Alzheimer's is perhaps the best known and most feared form of dementia. Early onset Alzheimer's disease, which often has a strong genetic component, may not be delayed with any lifestyle changes.
But late-life Alzheimer's, affecting people in their 80s and 90s, has only a minor genetic component and can be delayed or prevented with lifestyle changes -- especially if the changes begin in midlife, says Dr. Majid Fotuhi, chairman of the Neurology Institute for Brain Health and Fitness and a neurology professor at Johns Hopkins University School of Medicine.
I say, 'Dance'
Thursday, November 10, 2011
Lumosity's Human Cognition Project
Lumosity is a fascinating site. We've written about it before. The site partners with researchers at Stanford, UCSF, Harvard, and Columbia, among other prestigious universities, and also works with numerous health care organizations to provide cognitive training services.
I've played brain games on the site for a few years now, and, in addition to finding them fun, I believe they provide measurable brain benefits. You can target specific mental processes that you want to improve, and work on forming new brain cells by exercising your brain in certain ways. (No matter what brain exercises you select to concentrate on, do not neglect physical exercise. Get that blood flowing to the brain and you will only increase the benefits you will receive from exercising your brain.)
From the Lumosity newsletter:
Earlier this year, Lumosity introduced The Human Cognition Project, our groundbreaking effort to bring together scientists from 25 of the top neuroscience programs in the world.
We'd like to take this moment to remind our members of the flurry of scientific activity going on behind the scenes. Collaborators from institutions such as Stanford, Berkeley and Harvard are all pitching in with their own research projects, contributing towards the larger goal of crafting the most effective cognitive training programs in the world. There are over 35 research projectsrunning right now.
Members who play our games may not realize how much research, development, and testing goes on behind the scenes. We share our database on human cognition—the largest in the world—with university partners in order to broaden the scope of research possibilities. Researchers are actively exploring data collected from 15 million Lumosity users to better understand the determinants of cognitive performance and cognitive enhancement — all in an effort to make the world a smarter place.
Make sure you're a part of The Human Cognition Project: subscribe now to train with all 35+ games and donate your data to the scientific community! Although subscriptions cost a reasonable amount, if you can't pay to play right now, the Lumosity site also has several brain games you can play for free. Well worth a visit.
You can learn more at the Lumosity blog.
Thursday, November 03, 2011
Antidepressants for People With Dementia? Try Other Approaches First
This goes right along with Jack's revelation that the side effects of medications are often worse than the condition the medication is supposed to treat. He has also discovered an alarming number that can cause cognitive decline, a major worry for anyone who's already suffered a traumatic brain injury. After having a local university's School of Pharmacy study the list of 17 medications Jack was on and reading their report, he slowly began weaning himself off of most of them. He now takes just two. Jack worked with his doctors on this, although not all of them were in agreement. In the end it was Jack's choice, and it might not be the right one for everybody. The difference for Jack, however, has been amazing. He feels a lot better, feels more in control of his mental and emotional state, and now worries about all the other people being made sick by their prescribed medications.
From The Huffington Post:
Antidepressant medications may not be more effective than placebos in the treatment of depression in older adults who also have dementia, and the risks of antidepressant treatment may outweigh the benefits, particularly if the depression is not severe, according to two studies published this year.
Between 20 percent and 40 percent of people with dementia experience a diagnosable depressive disorder, nearly half major depression. This condition not only can be painful, it also increases risks of physical illness, disability and premature mortality. (3) In addition, it often results in decline in cognitive and functional capacity over and above the decline that results from dementia alone. Depression appears to have a particularly negative impact on "instrumental activities of daily living," including preparing meals, housework, managing finances, shopping, caring for others, etc.
Clearly, overcoming depression is important for people with dementia. But, recent studies have failed to demonstrate that antidepressants improve depression more than the attention received by participating in a research study.
One study, done with the support of the British National Health Service to evaluate the standard approach to treating depression in people with dementia, showed no benefit of antidepressants compared to placebos but did show more adverse side-effects. For this reason the authors strongly recommend a change in the standard treatment approach. Instead of starting with an antidepressant, they suggest that the first step should be "watchful waiting" while helping people with dementia and their caregivers to cope better with the difficulties typical of living with dementia. They suggest that many depressive episodes in dementia patients may resolve on their own. If not, psychotherapy provided by a specialist may help. The authors maintain that antidepressants should be reserved for depression that is severe or persistent.
Tuesday, November 01, 2011
Women hit harder as dementia deaths rise
From The Guardian:
Deaths from Alzheimer's disease and dementia are steadily rising in England and Wales, as cancer, heart attack and stroke deaths gradually come down.
The latest figures from the Office for National Statistics (ONS) show an 11.7% rise in dementia deaths in the last year, 2009-10, to a total of 25,106. More than two-thirds – 18,349 – were of women, in part because they live longer than men.
Alzheimer's and dementia are now the third leading cause of death for women, after heart disease and stroke. Falls in other, more preventable and treatable diseases are largely responsible for a 26% rise in dementia deaths over the five years between 2005 and 2010. In the same period, heart disease deaths dropped by 30% in women. Diseases of the urinary system – also linked to old age – increased by 8.1% in that time and lung cancer deaths rose by 3.5%, as smoking continued to take its long-term toll, but most other trends were down.Continue reading.
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