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Jack Sisson's TBI Blog

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From MedScape Today:
Despite the fact that depression after traumatic brain injury (TBI) affects up to 30% of patients — or approximately 360,000 individuals annually — an extensive analysis reveals a stunning lack of research into effective treatments.

In the systematic analysis, funded by the Agency for Healthcare Research and Quality (AHRQ), Melissa McPheeters, PhD, and colleagues from the Vanderbilt Evidence-Based Practice, Vanderbilt University Medical Center in Nashville, Tennessee, found that of 112 studies included in the meta-analysis only 2 studies addressed treatment for depression after TBI, and of these, only 1 was a randomized controlled trial.

"Clearly, we don't have nearly enough information about how to identify depression in this specific population of patients, and we certainly don't have enough information about treatment," Dr. McPheeters told Medscape Medical News.

According to the study, TBI is responsible for more than 1.2 million emergency department visits a year — a statistic that does not include TBI incurred during military service. In addition, this is likely an underestimation because many individuals with mild TBI do not present to the emergency department. The Centers for Disease Control and Prevention estimates that up to 75% of TBI is "mild."
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