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From DoctorsLounge:
In patients with Parkinson's disease (PD) who are effectively treated with deep brain stimulation (DBS), the natural progression of the disease's motor symptoms appears to stabilize over time, according to a study published in the November issue of the International Journal of Neuroscience. Michele Tagliati, M.D., of the Mount Sinai School of Medicine in New York City, and colleagues investigated the long-term progression of PD motor symptoms in 50 patients treated with subthalamic nucleus deep brain stimulation (STN-DBS).

The researchers found that motor scores measured without medication and with DBS off were virtually unchanged compared to the preoperative scores of patients up to five years after surgery. This result was seen in patients with both shorter (less than 11 years) and longer duration of PD prior to surgery. There was also no consistent deterioration from untreated baseline in any of the motor subscores, which included tremor, rigidity, bradykinesia, and axial symptoms.
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